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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL69385
Molecular formula	C23H29N3O3
IUPAC name	1-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Molecular weight	395.503
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.5
Synonyms	1-[2-[4-(4-Methoxyphenyl)piperazine-1-yl]ethyl]-3,4-dihydro-1H-2-benzopyran-6-carboxamide BDBM50064785 SCHEMBL7403625 1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
Inchi Key	OCFFXDBBLHVFSW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29N3O3/c1-28-20-5-3-19(4-6-20)26-13-11-25(12-14-26)10-8-22-21-7-2-18(23(24)27)16-17(21)9-15-29-22/h2-7,16,22H,8-15H2,1H3,(H2,24,27)
PubChem CID	23288790
ChEMBL	CHEMBL69385
IUPHAR	N/A
BindingDB	50064785
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
237689	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
237688	5-hydroxytryptamine receptor 1B	Q9N2B7	HTR1B	Gorilla gorilla gorilla (Western lowland gorilla)	390
237685	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
237687	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
237684	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
237686	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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