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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ML332
Molecular formula	C14H16ClF3N2O3S
IUPAC name	2-[2-chloro-N-methylsulfonyl-5-(trifluoromethyl)anilino]-N-(cyclopropylmethyl)acetamide
Molecular weight	384.798
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.7
Synonyms	CHEMBL2208405 MLS004580679 1415834-37-5 VU0400100-2 BDBM50402787 KB-274635 NCGC00386817-01 2-{N-[2-chloro-5-(trifluoromethyl)phenyl]methanesulfonamido}-N-(cyclopropylmethyl)acetamide ZINC95562487 SMR003382964 [ Show all ]
Inchi Key	SWDFZDHXQCXDGL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16ClF3N2O3S/c1-24(22,23)20(8-13(21)19-7-9-2-3-9)12-6-10(14(16,17)18)4-5-11(12)15/h4-6,9H,2-3,7-8H2,1H3,(H,19,21)
PubChem CID	60210882
ChEMBL	CHEMBL2208405
IUPHAR	N/A
BindingDB	50402787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
324761	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
324756	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
324759	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
324760	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
324753	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
324754	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
324755	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
324757	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
324758	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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