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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3401177
Molecular formula	C19H14FN3O2
IUPAC name	6-(4-fluorophenyl)-2-(phenoxymethyl)imidazo[1,2-c]pyrimidin-5-one
Molecular weight	335.338
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50064463 SCHEMBL12491532 SCXUQPKHWUFDNI-UHFFFAOYSA-N 6-(4-fluoro-phenyl)-2-phenoxymethyl-6H-imidazo[1,2-c]pyrimidin-5-one
Inchi Key	SCXUQPKHWUFDNI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H14FN3O2/c20-14-6-8-16(9-7-14)22-11-10-18-21-15(12-23(18)19(22)24)13-25-17-4-2-1-3-5-17/h1-12H,13H2
PubChem CID	68290572
ChEMBL	CHEMBL3401177
IUPHAR	N/A
BindingDB	50064463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
454052	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
454050	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
454046	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
454048	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
454045	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
454051	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
454047	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
454049	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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