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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL449347
Molecular formula	C28H31NO2
IUPAC name	(2R,3R)-2-benzhydryl-3-[(2-methoxyphenyl)methoxy]-1-azabicyclo[2.2.2]octane
Molecular weight	413.561
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.6
Synonyms	(2R,3R)-2-(2,2-Diphenyl-ethyl)-3-(2-methoxy-benzyloxy)-1-aza-bicyclo[2.2.2]octane BDBM50280460
Inchi Key	QXSIOQKZUFLLLE-VSGBNLITSA-N
Inchi ID	InChI=1S/C28H31NO2/c1-30-25-15-9-8-14-24(25)20-31-28-23-16-18-29(19-17-23)27(28)26(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-15,23,26-28H,16-20H2,1H3/t27-,28-/m1/s1
PubChem CID	44368326
ChEMBL	CHEMBL449347
IUPHAR	N/A
BindingDB	50280460
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
289452	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
289451	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
289450	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407
289453	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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