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You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Substance-P receptor
Species	Rattus norvegicus (Rat)
Gene	Tacr1
Synonym	TAC1R Substance P receptor SPR NK1R NK1 receptor NK-1R NK-1 receptor neurokinin receptor 1 Tachykinin receptor 1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	407
Amino acid sequence	MDNVLPMDSDLFPNISTNTSESNQFVQPTWQIVLWAAAYTVIVVTSVVGNVVVIWIILAHKRMRTVTNYFLVNLAFAEACMAAFNTVVNFTYAVHNVWYYGLFYCKFHNFFPIAALFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYLKKFIQQVYLASMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQSSVYKVSRLETTISTVVGAHEEEPEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA
UniProt	P14600
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4027
IUPHAR	360
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
1105	CHEMBL143156	C27H30F6N2O2	528.539	9 / 0	5.6	No
1515	CHEMBL556537	C70H89F6N11O15	1438.53	22 / 14	5.8	No
1834	CHEMBL2304114	C97H126N18O19S	1880.24	21 / 15	7.8	No
2433	CHEMBL438422	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2434	CHEMBL413304	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2435	CHEMBL428315	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2436	CHEMBL384274	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2437	CHEMBL409406	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2438	CHEMBL411977	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2439	CHEMBL385507	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2440	CHEMBL410402	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2441	CHEMBL216901	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2442	CHEMBL414911	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2443	CHEMBL386194	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2444	CHEMBL415827	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2445	CHEMBL407601	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2446	CHEMBL384088	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2447	CHEMBL217596	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2448	CHEMBL262941	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2449	CHEMBL439278	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2450	CHEMBL409993	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2451	CHEMBL266426	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441770	CHEMBL411422	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2452	CHEMBL385149	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2453	CHEMBL439058	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2454	CHEMBL276698	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2455	CHEMBL406617	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2456	CHEMBL441748	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441771	CHEMBL444093	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441772	CHEMBL411281	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2457	CHEMBL439070	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2458	CHEMBL411622	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2459	CHEMBL408250	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2460	CHEMBL383867	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2461	CHEMBL415443	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2462	CHEMBL263928	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441773	CHEMBL406623	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2463	CHEMBL405236	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2464	CHEMBL403499	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441774	CHEMBL425455	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441775	CHEMBL266075	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2465	CHEMBL264585	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2466	CHEMBL427648	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2467	CHEMBL265852	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441776	CHEMBL264328	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2468	CHEMBL415793	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2469	CHEMBL413622	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2470	CHEMBL438754	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2471	CHEMBL264557	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2472	CHEMBL414127	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2473	CHEMBL408503	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2474	CHEMBL386130	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2475	CHEMBL424913	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2476	CHEMBL217161	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2477	CHEMBL407657	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441777	CHEMBL385148	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2478	CHEMBL217432	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2479	CHEMBL426159	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2480	CHEMBL384394	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441778	CHEMBL384314	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2481	CHEMBL438466	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2482	CHEMBL269312	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2483	CHEMBL405064	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2484	CHEMBL407872	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2485	CHEMBL409778	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2486	CHEMBL414529	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2487	Substance P	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2499	CHEMBL264713	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2500	CHEMBL410796	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2501	CHEMBL267139	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2502	CHEMBL412919	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441779	CHEMBL413406	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2503	CHEMBL410018	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2504	CHEMBL444112	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2505	CHEMBL216569	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2506	CHEMBL262964	C63H98N18O13S	1347.65	17 / 15	-2.3	No
441780	CHEMBL405306	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2507	CHEMBL404964	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2508	CHEMBL262682	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2509	CHEMBL410227	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2510	CHEMBL406689	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2511	CHEMBL276697	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2512	CHEMBL267672	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2513	CHEMBL415529	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2514	CHEMBL265618	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2515	CHEMBL415013	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2516	CHEMBL405514	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2517	CHEMBL383886	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2518	CHEMBL217325	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2519	CHEMBL407871	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2520	CHEMBL415442	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2521	CHEMBL402885	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2522	CHEMBL436736	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2523	CHEMBL438091	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2524	CHEMBL405950	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2525	CHEMBL262846	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2526	CHEMBL262688	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2527	CHEMBL415147	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2528	CHEMBL430253	C63H98N18O13S	1347.65	17 / 15	-2.3	No
2529	CHEMBL266517	C63H98N18O13S	1347.65	17 / 15	-2.3	No

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