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| Name | Substance-K receptor |
|---|---|
| Species | Mesocricetus auratus (Golden hamster) |
| Gene | TACR2 |
| Synonym | Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2 |
| Disease | N/A for non-human GPCRs |
| Length | 384 |
| Amino acid sequence | MGGRAIVTDTNIFSGLESNTTGVTAFSMPAWQLALWATAYLGLVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPITKATIAGIWLVALALASPQCFYSTITVDQGATKCVVAWPNDNGGKMLLLYHLVVFVLVYFLPLVVMFVAYSVIGLTLWKRAVPRHQAHGANLRHLHAKKKFVKAMVLVVLTFAICWLPYHLYFILGSFQKDIYYRKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTRTPSLSRRVNRCHTKETLFMTADMTHSEATNGQVGSPQDVEPAAP |
| UniProt | P51144 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2304405 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1217 |  CHEMBL150346 | C23H24N2O2 | 360.457 | 2 / 1 | 3.2 | Yes |
| 2489 |  Substance P | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
| 5219 |  CHEMBL296014 | C32H47N3O5 | 553.744 | 5 / 4 | 5.6 | No |
| 7867 |  CHEMBL98977 | C18H21ClN6O | 372.857 | 6 / 2 | 3.8 | Yes |
| 12314 |  CHEMBL98760 | C22H24ClN5O2 | 425.917 | 6 / 2 | 4.2 | Yes |
| 12966 |  CHEMBL2370585 | C66H83N13O17 | 1330.46 | 19 / 19 | -1.8 | No |
| 16018 |  CHEMBL152239 | C27H29FN2 | 400.541 | 3 / 1 | 5.5 | No |
| 16947 |  CHEMBL327531 | C16H17ClN6O | 344.803 | 6 / 2 | 3.1 | Yes |
| 20474 |  CHEMBL329888 | C46H58N8O11S | 931.075 | 13 / 11 | 0.6 | No |
| 20865 |  CHEMBL449091 | C45H64N10O10 | 905.067 | 10 / 10 | 0.2 | No |
| 21974 |  L-Serine,N-[1-oxo-3-(2-pentylphenyl)propyl]-L-threonyl-(aE)-a,b-didehydro-N-methyltyrosyl-L-leucyl-D-phenylalanyl-L-allothreonyl-L-asparaginyl-,(7®1)-lactone | C54H72N8O13 | 1041.21 | 13 / 10 | 4.9 | No |
| 23630 |  CHEMBL318254 | C18H21ClN6O | 372.857 | 6 / 2 | 3.9 | Yes |
| 25202 |  CHEMBL128854 | C38H64N8O9 | 776.977 | 11 / 9 | -0.7 | No |
| 29857 |  CHEMBL339941 | C35H58N8O9 | 734.896 | 11 / 10 | -2.0 | No |
| 30743 |  CHEMBL412621 | C60H64N10O12 | 1117.23 | 13 / 14 | 3.2 | No |
| 36141 |  PD157672 | C32H47N5O5 | 581.758 | 5 / 5 | 4.5 | No |
| 37243 |  CHEMBL307433 | C45H66N10O10 | 907.083 | 10 / 10 | 0.8 | No |
| 40541 |  MEN-10627 | C38H48N8O7S | 760.911 | 8 / 8 | 2.0 | No |
| 43090 |  CHEMBL118328 | C20H22N4O2 | 350.422 | 3 / 4 | 0.8 | Yes |
| 44570 |  CHEMBL339615 | C34H56N8O9S | 752.929 | 12 / 10 | -2.7 | No |
| 46025 |  CHEMBL332820 | C40H57N9O6 | 759.953 | 8 / 9 | 1.5 | No |
| 49586 |  CHEMBL387199 | C56H64N10O11S | 1085.25 | 13 / 13 | 2.6 | No |
| 63284 |  CHEMBL97520 | C20H19ClN4O3 | 398.847 | 7 / 1 | 4.0 | Yes |
| 64536 |  CHEMBL433192 | C38H51N9O7 | 745.882 | 8 / 9 | 0.2 | No |
| 64677 |  CHEMBL412189 | C60H64N10O11 | 1101.23 | 12 / 13 | 3.5 | No |
| 65550 |  CHEMBL268563 | C61H67N11O10 | 1114.27 | 11 / 13 | 3.3 | No |
| 68121 |  CHEMBL2369767 | C43H59N9O9 | 845.999 | 9 / 9 | 1.3 | No |
| 68235 |  CHEMBL327457 | C48H59N9O10S | 954.113 | 12 / 11 | 1.1 | No |
| 70782 |  CHEMBL421062 | C40H56N8O6 | 744.938 | 7 / 8 | 3.0 | No |
| 72876 |  CHEMBL299377 | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 73431 |  CHEMBL441181 | C50H60N10O11S | 1009.15 | 13 / 13 | 0.3 | No |
| 78382 |  Substance P (5-11) | C41H60N10O9S | 869.052 | 11 / 10 | -0.5 | No |
| 78510 |  CHEMBL36402 | C40H54N8O9S | 822.979 | 10 / 9 | 1.7 | No |
| 80401 |  CHEMBL438716 | C48H60N12O11 | 981.081 | 13 / 14 | -1.4 | No |
| 80403 |  CHEMBL266526 | C48H60N12O11 | 981.081 | 13 / 14 | -1.4 | No |
| 81429 |  CP 96345 | C28H32N2O | 412.577 | 3 / 1 | 5.4 | No |
| 81442 |  CHEMBL346154 | C28H32N2O | 412.577 | 3 / 1 | 5.4 | No |
| 81448 |  CHEMBL419500 | C28H32N2O | 412.577 | 3 / 1 | 5.4 | No |
| 83592 |  CHEMBL306072 | C43H62N10O10S | 911.089 | 11 / 10 | -0.5 | No |
| 85464 |  CHEMBL121271 | C47H56N8O6 | 829.015 | 7 / 8 | 4.5 | No |
| 96043 |  CHEMBL336849 | C37H62N8O9 | 762.95 | 11 / 9 | -1.2 | No |
| 105154 |  CHEMBL292766 | C27H27N3O3 | 441.531 | 3 / 3 | 4.7 | Yes |
| 110733 |  CHEMBL120790 | C31H31N3O3 | 493.607 | 3 / 1 | 5.9 | No |
| 112529 |  NEUROKININ A | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 112530 |  Substance K | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 112586 |  CHEMBL406487 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 112590 |  CHEMBL429340 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 112592 |  CHEMBL217365 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 116210 |  CHEMBL295301 | C33H48N4O5 | 580.77 | 5 / 4 | 5.3 | No |
| 125936 |  CHEMBL332872 | C38H50N8O8 | 746.866 | 9 / 9 | -1.4 | No |
| 131794 |  CHEMBL439287 | C62H65N11O11 | 1140.27 | 12 / 14 | 3.7 | No |
| 137269 |  CHEMBL98929 | C19H22ClN5O2 | 387.868 | 6 / 1 | 3.0 | Yes |
| 142009 |  CHEMBL339591 | C42H64N8O9 | 825.021 | 11 / 9 | -0.5 | No |
| 143276 |  CHEMBL45340 | C29H40F2N4O4 | 546.66 | 6 / 4 | 5.2 | No |
| 143626 |  CHEMBL407328 | C57H68N14O10 | 1109.26 | 12 / 15 | 0.1 | No |
| 159646 |  CHEMBL152011 | C22H28N2O | 336.479 | 3 / 1 | 3.9 | Yes |
| 169540 |  CHEMBL346633 | C28H32N2 | 396.578 | 2 / 1 | 5.8 | No |
| 171323 |  CHEMBL3215393 | C72H87N13O17 | 1406.56 | 19 / 19 | 0.3 | No |
| 179305 |  CHEMBL333515 | C44H62N8O6 | 799.03 | 7 / 7 | 4.9 | No |
| 181178 |  CHEMBL267409 | C53H58N10O11 | 1011.11 | 12 / 13 | 1.6 | No |
| 183847 |  CHEMBL263743 | C51H64N12O11 | 1021.15 | 13 / 13 | -0.7 | No |
| 184790 |  CHEMBL263985 | C59H68N14O10 | 1133.28 | 12 / 15 | 1.2 | No |
| 184792 |  CHEMBL216897 | C59H68N14O10 | 1133.28 | 12 / 15 | 1.2 | No |
| 188045 |  CHEMBL413730 | C51H64N10O14 | 1041.13 | 16 / 15 | -0.7 | No |
| 189684 |  CHEMBL128175 | C35H58N8O9 | 734.896 | 11 / 10 | -2.0 | No |
| 189896 |  CHEMBL153042 | C28H31ClN2 | 431.02 | 2 / 1 | 6.5 | No |
| 193907 |  CHEMBL2369766 | C43H61N9O9 | 848.015 | 9 / 9 | 2.0 | No |
| 196878 |  CHEMBL356912 | C27H29ClN2 | 416.993 | 2 / 1 | 6.0 | No |
| 199387 |  CHEMBL121571 | C39H54N8O6S | 762.971 | 8 / 8 | 2.3 | No |
| 203260 |  CHEMBL152055 | C20H24N2 | 292.426 | 2 / 1 | 3.4 | Yes |
| 207619 |  CHEMBL333027 | C48H63N9O8 | 894.087 | 9 / 9 | 3.6 | No |
| 210346 |  CHEMBL32248 | C28H28N4O4 | 484.556 | 4 / 4 | 3.5 | Yes |
| 563933 |  AC1MMLX8 | C28H28N4O4 | 484.556 | 4 / 4 | 3.5 | Yes |
| 214331 |  CHEMBL421071 | C43H58N8O7 | 798.986 | 7 / 8 | 4.2 | No |
| 214445 |  CHEMBL385914 | C55H63N11O11 | 1054.18 | 13 / 14 | -1.5 | No |
| 214577 |  CHEMBL110219 | C33H38Cl2N4O2 | 593.593 | 4 / 1 | 5.9 | No |
| 218709 |  MEN-10414 | C40H46N8O8 | 766.856 | 9 / 10 | -0.4 | No |
| 219697 |  CHEMBL97958 | C17H19ClN6O | 358.83 | 6 / 2 | 3.5 | Yes |
| 223771 |  Neurokinin B | C55H79N13O14S2 | 1210.43 | 18 / 14 | -1.6 | No |
| 230678 |  CHEMBL262647 | C54H70N12O10 | 1047.23 | 13 / 14 | -2.0 | No |
| 237945 |  CHEMBL341065 | C35H56N8O10 | 748.879 | 11 / 10 | -2.3 | No |
| 238847 |  CHEMBL331480 | C46H61N9O7 | 852.05 | 9 / 9 | 2.6 | No |
| 241380 |  CHEMBL262731 | C35H58N8O9 | 734.896 | 11 / 10 | -2.1 | No |
| 243983 |  CHEMBL340847 | C35H57N7O9 | 719.881 | 10 / 9 | -0.8 | No |
| 253348 |  CHEMBL337970 | C38H56N8O9 | 768.913 | 11 / 10 | -1.8 | No |
| 254738 |  CHEMBL129301 | C40H66N8O10 | 819.014 | 11 / 9 | -0.8 | No |
| 258319 |  CHEMBL409334 | C35H58N8O9 | 734.896 | 11 / 10 | -2.0 | No |
| 259146 |  Saredutant | C31H35Cl2N3O2 | 552.54 | 3 / 1 | 5.9 | No |
| 259161 |  CHEMBL56835 | C31H35Cl2N3O2 | 552.54 | 3 / 1 | 5.9 | No |
| 271040 |  CHEMBL341015 | C35H58N8O9 | 734.896 | 11 / 10 | -2.0 | No |
| 272976 |  CHEMBL340880 | C36H60N8O9 | 748.923 | 11 / 10 | -2.1 | No |
| 279622 |  CHEMBL97204 | C19H17ClN4O3 | 384.82 | 7 / 2 | 3.7 | Yes |
| 284351 |  CHEMBL412982 | C57H68N12O10 | 1081.24 | 12 / 14 | 1.1 | No |
| 289451 |  CHEMBL449347 | C28H31NO2 | 413.561 | 3 / 0 | 5.6 | No |
| 294874 |  CHEMBL334186 | C46H59N9O7 | 850.034 | 8 / 9 | 2.4 | No |
| 295898 |  CHEMBL346626 | C29H33ClN2 | 445.047 | 2 / 1 | 6.8 | No |
| 310210 |  CHEMBL330810 | C43H54N8O6 | 778.955 | 7 / 8 | 3.3 | No |
| 310229 |  CHEMBL128521 | C36H60N8O9 | 748.923 | 11 / 9 | -1.6 | No |
| 315995 |  CHEMBL345711 | C28H29F3N2 | 450.549 | 5 / 1 | 6.3 | No |
| 324172 |  CHEMBL357717 | C27H30N2 | 382.551 | 2 / 1 | 5.4 | No |
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