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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL153042
Molecular formula	C28H31ClN2
IUPAC name	(2R,3R)-2-benzhydryl-N-[2-(2-chlorophenyl)ethyl]-1-azabicyclo[2.2.2]octan-3-amine
Molecular weight	431.02
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM50280465 [2-(2-Chloro-phenyl)-ethyl]-[(2R,3R)-2-(2,2-diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-amine
Inchi Key	LKTXZRZNGUFCKQ-VSGBNLITSA-N
Inchi ID	InChI=1S/C28H31ClN2/c29-25-14-8-7-9-21(25)15-18-30-27-24-16-19-31(20-17-24)28(27)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-14,24,26-28,30H,15-20H2/t27-,28-/m1/s1
PubChem CID	15037920
ChEMBL	CHEMBL153042
IUPHAR	N/A
BindingDB	50280465
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
189898	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
189896	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
189897	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407
189899	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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