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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Substance P (5-11)
Molecular formula	C41H60N10O9S
IUPAC name	(2S)-2-amino-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide
Molecular weight	869.052
Hydrogen bond acceptor	11
Hydrogen bond donor	10
XlogP	-0.5
Synonyms	CHEMBL311405 Substance P, 1-de-L-arginine-2-de-L-proline-3-de-L-lysine-4-de-L-proline- 1-Dearginyl-2,4-deprolyl-3-delysine-substance P 51165-09-4 SCHEMBL11309707 BDBM50283252 Substance P C-terminal heptapeptide (2S)-2-amino-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl] 1-Des-arg-2,4-des-pro-3-des-lys-substance P CTK4J3779 Substance P, dearginyl(1)-deprolyl(2,4)-delysine(3)- AC1L4RN3 Spcthp Substance P(5-11) (S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carbamoyl-butyrylamino)-4-carbamoyl-butyrylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoic acid ((S)-1-carbamoyl-3-methylsulfanyl-propyl)-amide l-glutaminyl-l-glutaminyl-l-phenylalanyl-l-phenylalanylglycyl-l-leucyl-l-methioninamide ZINC150357932 AC1Q5IQB [ Show all ]
Inchi Key	FHHJIELOJQJHCG-JNRWAQIZSA-N
Inchi ID	InChI=1S/C41H60N10O9S/c1-24(2)20-30(40(59)48-28(36(45)55)18-19-61-3)47-35(54)23-46-38(57)31(21-25-10-6-4-7-11-25)50-41(60)32(22-26-12-8-5-9-13-26)51-39(58)29(15-17-34(44)53)49-37(56)27(42)14-16-33(43)52/h4-13,24,27-32H,14-23,42H2,1-3H3,(H2,43,52)(H2,44,53)(H2,45,55)(H,46,57)(H,47,54)(H,48,59)(H,49,56)(H,50,60)(H,51,58)/t27-,28-,29-,30-,31-,32-/m0/s1
PubChem CID	162632
ChEMBL	CHEMBL311405
IUPHAR	N/A
BindingDB	50283252
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78380	Neuromedin-K receptor	P30098	TACR3	Cavia porcellus (Guinea pig)	440
78382	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
78381	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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