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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL346154
Molecular formula	C28H32N2O
IUPAC name	(2R,3R)-2-benzhydryl-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
Molecular weight	412.577
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.4
Synonyms	PDSP1_000655 BDBM50280461 ((2R,3R)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine CP-96,344 (2R,3R)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine AC1LAKZR SCHEMBL5378537 (2R,3R)-2-benzhydryl-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine CP-96344 135095-42-0 B7213 ZINC36324026 (2R,3R)-2-benzhydryl-N-[(2-methoxyphenyl)methyl]quinuclidin-3-amine [ Show all ]
Inchi Key	FLNYLINBEZROPL-VSGBNLITSA-N
Inchi ID	InChI=1S/C28H32N2O/c1-31-25-15-9-8-14-24(25)20-29-27-23-16-18-30(19-17-23)28(27)26(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-15,23,26-29H,16-20H2,1H3/t27-,28-/m1/s1
PubChem CID	490428
ChEMBL	CHEMBL346154
IUPHAR	N/A
BindingDB	50280461
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
81441	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
81442	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
81438	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407
81439	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407
81440	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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