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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL152011
Molecular formula	C22H28N2O
IUPAC name	(2R,3R)-2-benzyl-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
Molecular weight	336.479
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	(2-Methoxy-benzyl)-((2R,3R)-2-phenethyl-1-aza-bicyclo[2.2.2]oct-3-yl)-amine BDBM50280463 2alpha-Benzyl-N-(2-methoxybenzyl)quinuclidin-3alpha-amine
Inchi Key	JTNZAZWXIUSVNY-IFMALSPDSA-N
Inchi ID	InChI=1S/C22H28N2O/c1-25-21-10-6-5-9-19(21)16-23-22-18-11-13-24(14-12-18)20(22)15-17-7-3-2-4-8-17/h2-10,18,20,22-23H,11-16H2,1H3/t20-,22-/m1/s1
PubChem CID	14986146
ChEMBL	CHEMBL152011
IUPHAR	N/A
BindingDB	50280463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
159643	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
159646	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
159644	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407
159645	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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