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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL8839
Molecular formula	C7H9NO4S
IUPAC name	(1R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
Molecular weight	203.212
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.5
Synonyms	2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylicacid, 4-amino-, (1R,4S,5S,6S)- DTXSID40436647 (1beta,5beta)-4-Amino-2-thiabicyclo[3.1.0]hexane-4beta,6beta-dicarboxylic acid 222529-89-7 SCHEMBL2450641 BDBM50074750 (1R,4S,5S,6S)-4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid CTK1A0220 4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxylic acid [ Show all ]
Inchi Key	QBHIOYZCUZBIEN-MDASVERJSA-N
Inchi ID	InChI=1S/C7H9NO4S/c8-7(6(11)12)1-13-4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
PubChem CID	10198133
ChEMBL	CHEMBL8839
IUPHAR	N/A
BindingDB	50074750
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
274089	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
274087	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
274086	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
274090	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
274088	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
274091	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
274093	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
274092	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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