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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3897426
Molecular formula	C31H35FN4O2
IUPAC name	N-[(4-cyanophenyl)methyl]-6-[4-[4-fluoro-2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Molecular weight	514.645
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50193415
Inchi Key	PYMZBBSVTWGBTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H35FN4O2/c1-38-28-13-10-26(11-14-28)29-21-27(32)12-15-30(29)36-19-17-35(18-20-36)16-4-2-3-5-31(37)34-23-25-8-6-24(22-33)7-9-25/h6-15,21H,2-5,16-20,23H2,1H3,(H,34,37)
PubChem CID	134134456
ChEMBL	CHEMBL3897426
IUPHAR	N/A
BindingDB	50193415
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
551287	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
551286	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
551285	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448
551288	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
551289	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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