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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3747116
Molecular formula	C19H16FN3O2
IUPAC name	5-(4-fluorophenyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	337.354
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50134466 PVXQBLCMLZKSAX-UHFFFAOYSA-N 2-(benzyloxy)-5-(4-fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one SCHEMBL16270155
Inchi Key	PVXQBLCMLZKSAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16FN3O2/c20-15-6-8-16(9-7-15)22-10-11-23-17(19(22)24)12-18(21-23)25-13-14-4-2-1-3-5-14/h1-9,12H,10-11,13H2
PubChem CID	72714783
ChEMBL	CHEMBL3747116
IUPHAR	N/A
BindingDB	50134466
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
529235	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
529239	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
529233	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
529234	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
529237	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
529236	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
529240	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
529238	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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