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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL262416
Molecular formula	C8H12N2O4
IUPAC name	(2R)-2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid
Molecular weight	200.194
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-2.9
Synonyms	(R)-Homo-AMPA BDBM50060718 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid (R)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid
Inchi Key	NZDIZJGEDFARSV-ZCFIWIBFSA-N
Inchi ID	InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t6-/m1/s1
PubChem CID	10774389
ChEMBL	CHEMBL262416
IUPHAR	N/A
BindingDB	50060718
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
235603	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
235605	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
564679	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
235601	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
235598	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
235604	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
235599	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
235602	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915

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