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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	homo-AMPA
Molecular formula	C8H12N2O4
IUPAC name	2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid
Molecular weight	200.194
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-2.9
Synonyms	GTPL3359 HomoAMPA 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid BDBM50052551 SR-01000597464 2-amino-4-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)butanoic acid CTK8G0203 179169-88-1 a-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolebutanoic acid HMS3267O13 NCGC00024946-02 2-Amino-4-(3-hydroxy-5-methylisoxazole-4-yl)butyric acid SR-01000597464-1 D0L0YF 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid AC1N6KQF SCHEMBL3731488 2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid CHEMBL107768 [ Show all ]
Inchi Key	NZDIZJGEDFARSV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)
PubChem CID	4236420
ChEMBL	CHEMBL107768
IUPHAR	3359
BindingDB	50052551
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
235591	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
235593	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
235592	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
235597	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
235594	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
235595	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
235590	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
235596	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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