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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MTEP
Molecular formula	C11H8N2S
IUPAC name	2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole
Molecular weight	200.259
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	2.3
Synonyms	3-[2-(2-Methylthiazol-4-yl)ethynyl]pyridine CHEMBL292065 KB-274670 3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine D09YDQ Pyridine, 3-[(2-methyl-4-thiazolyl)ethynyl]- 3-[(2-methyl-4-thiazolyl)ethynyl]pyridine BDBM50122758 GTPL3336 2-methyl-4-(pyridin-3-ylethynyl)thiazole 329205-68-7 CTK1B8867 mGluR5 Antagonist, MTEP 3-(2-Methyl-thiazol-4-ylethynyl)-pyridine ACN-027361 DTXSID30430775 SCHEMBL187254 3-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine IN1238 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine D00JLE 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine API0006876 FCH3417361 ZINC1489321 [ Show all ]
Inchi Key	NRBNGHCYDWUVLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H8N2S/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10/h2-3,6-8H,1H3
PubChem CID	9794218
ChEMBL	CHEMBL292065
IUPHAR	3336
BindingDB	50122758
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
229982	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
491470	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
229985	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
229983	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
229979	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
229980	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
229981	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
229984	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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