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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	JNJ-39319202
Molecular formula	C30H38N4O5S2
IUPAC name	N-[(4R)-4-(3,4-dimethoxyphenyl)-4-[7-(4-ethylpiperazin-1-yl)-3-oxo-1H-isoindol-2-yl]butyl]thiophene-2-sulfonamide
Molecular weight	598.777
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.1
Synonyms	ZINC43204087 GTPL9437 (R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpiperazin-1-yl)-1-oxoisoindolin-2-yl)butyl)thiophene-2-sulfonamide N-[(4R)-4-(3,4-dimethoxyphenyl)-4-[7-(4-ethylpiperazin-1-yl)-3-oxo-1H-isoindol-2-yl]butyl]thiophene-2-sulfonamide CHEMBL567713 1093069-95-4 SCHEMBL2347581 BDBM50302257 compound 7a [PMID: 19731961] KB-78001 [ Show all ]
Inchi Key	MWCLCGKVMLYVJI-RUZDIDTESA-N
Inchi ID	InChI=1S/C30H38N4O5S2/c1-4-32-15-17-33(18-16-32)26-9-5-8-23-24(26)21-34(30(23)35)25(22-12-13-27(38-2)28(20-22)39-3)10-6-14-31-41(36,37)29-11-7-19-40-29/h5,7-9,11-13,19-20,25,31H,4,6,10,14-18,21H2,1-3H3/t25-/m1/s1
PubChem CID	25126427
ChEMBL	CHEMBL567713
IUPHAR	9437
BindingDB	50302257
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
215721	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
215716	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
215720	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
215719	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
215717	Urotensin-2 receptor	Q9UKP6	UTS2R	Homo sapiens (Human)	389
215718	Urotensin-2 receptor	P49684	Uts2r	Rattus norvegicus (Rat)	386

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