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| Name | Urotensin-2 receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Uts2r |
| Synonym | UT receptor urotensin II receptor UR-II-R UR-2-R UII-R1 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 386 |
| Amino acid sequence | MALSLESTTSFHMLTVSGSTVTELPGDSNVSLNSSWSGPTDPSSLKDLVATGVIGAVLSAMGVVGMVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIIATYVTKDWHFGDVGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLVLGTWLLALLLTLPMMLAIQLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYVRLARAYWLSQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHEAMPLTPETARIVNYLTTCLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCHSPGSPGSFLPSRVHLQQDSGRSLSSSSQQATETLMLSPVPRNGALL |
| UniProt | P49684 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4921 |
| IUPHAR | 365 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 823 |  CHEMBL571683 | C30H33N3O4 | 499.611 | 6 / 0 | 4.6 | Yes |
| 824 |  CHEMBL577518 | C30H33N3O4 | 499.611 | 6 / 0 | 4.6 | Yes |
| 826 |  CHEMBL566389 | C30H33N3O4 | 499.611 | 6 / 0 | 4.6 | Yes |
| 3963 |  CHEMBL237877 | C24H29N3O3 | 407.514 | 4 / 0 | 2.5 | Yes |
| 7100 |  477313-09-0 | C19H21Cl2NO2 | 366.282 | 3 / 1 | N/A | N/A |
| 9210 |  SB-436811 | C23H29Cl2N3O2 | 450.404 | 4 / 1 | 4.5 | Yes |
| 13958 |  CHEMBL1165735 | C52H69N11O11S2 | 1088.31 | 15 / 13 | 0.0 | No |
| 18655 |  CHEMBL238066 | C33H43ClN4O5 | 611.18 | 6 / 1 | 4.9 | No |
| 26677 |  CHEMBL1165767 | C51H66N12O12S2 | 1103.28 | 16 / 14 | -2.5 | No |
| 29749 |  SB 706375 | C20H22BrF3N2O5S | 539.364 | 10 / 1 | 4.2 | No |
| 37112 |  CHEMBL1165797 | C66H86N14O16S2 | 1395.62 | 20 / 17 | -3.4 | No |
| 39702 |  CHEMBL1163473 | C46H59N9O9S2 | 946.152 | 13 / 11 | 0.5 | No |
| 44794 |  CHEMBL578207 | C29H38N6O5S | 582.72 | 9 / 2 | 2.6 | No |
| 45368 |  CHEMBL565416 | C29H36N4O5S2 | 584.75 | 9 / 1 | 3.5 | No |
| 50160 |  CHEMBL569689 | C33H40N4O6S | 620.765 | 9 / 1 | 4.0 | No |
| 50621 |  CHEMBL500949 | C56H69N11O12S2 | 1152.35 | 16 / 12 | 1.9 | No |
| 54723 |  CHEMBL565388 | C38H44N6O5 | 664.807 | 8 / 2 | 5.0 | No |
| 56104 |  CHEMBL3104467 | C48H63N9O10S2 | 990.205 | 14 / 10 | -0.2 | No |
| 56106 |  CHEMBL3104466 | C48H63N9O10S2 | 990.205 | 14 / 10 | -0.2 | No |
| 56385 |  CHEMBL584545 | C32H38N4O4 | 542.68 | 7 / 1 | 4.0 | No |
| 61531 |  CHEMBL567759 | C37H44N6O6S | 700.855 | 10 / 2 | 4.7 | No |
| 444307 |  CHEMBL3315140 | C56H70N10O11S2 | 1123.35 | 15 / 12 | -0.7 | No |
| 471464 |  CHEMBL3577310 | C32H34N4O4 | 538.648 | 6 / 5 | 1.9 | No |
| 471466 |  CHEMBL3577309 | C32H34N4O4 | 538.648 | 6 / 5 | 1.9 | No |
| 69797 |  CHEMBL567075 | C31H38N4O4S | 562.729 | 7 / 1 | 4.4 | No |
| 72235 |  CHEMBL3104639 | C47H62IN9O10S2 | 1104.09 | 14 / 11 | 0.7 | No |
| 73664 |  CHEMBL566187 | C28H29N3O4 | 471.557 | 6 / 0 | 3.8 | Yes |
| 82245 |  CHEMBL504097 | C57H72N10O10S2 | 1121.38 | 14 / 12 | 2.4 | No |
| 91873 |  CHEMBL566144 | C30H34N4O4 | 514.626 | 7 / 1 | 3.3 | No |
| 474746 |  CHEMBL3577304 | C30H30N4O4 | 510.594 | 6 / 4 | 2.3 | No |
| 96239 |  CHEMBL237879 | C34H45ClN4O4 | 609.208 | 5 / 1 | 5.1 | No |
| 96388 |  CHEMBL524855 | C58H72N10O10S2 | 1133.39 | 14 / 12 | 2.5 | No |
| 98344 |  CHEMBL392166 | C33H44N4O5 | 576.738 | 6 / 1 | 4.2 | No |
| 445655 |  CHEMBL3315142 | C56H70N10O11S2 | 1123.35 | 15 / 12 | -0.7 | No |
| 108141 |  CHEMBL501579 | C56H70N10O10S2 | 1107.36 | 14 / 12 | 2.1 | No |
| 476682 |  CHEMBL3577308 | C29H30N4O4 | 498.583 | 6 / 5 | 1.2 | Yes |
| 476685 |  CHEMBL3577307 | C29H30N4O4 | 498.583 | 6 / 5 | 1.2 | Yes |
| 112390 |  CHEMBL1163475 | C45H54N8O8S2 | 899.095 | 11 / 9 | 2.8 | No |
| 113596 |  CHEMBL437430 | C64H85N13O18S2 | 1388.58 | 22 / 17 | -4.5 | No |
| 476898 |  CHEMBL593662 | C64H85N13O18S2 | 1388.58 | 22 / 17 | -4.5 | No |
| 446163 |  urotensin-II | C64H85N13O18S2 | 1388.58 | 22 / 17 | -4.5 | No |
| 115591 |  CHEMBL508811 | C57H71N11O12S2 | 1166.38 | 16 / 12 | 2.3 | No |
| 115770 |  CHEMBL237878 | C29H31N3O3 | 469.585 | 4 / 1 | 3.8 | Yes |
| 115977 |  Human U-II | C62H86N14O17S2 | 1363.57 | 21 / 20 | -4.8 | No |
| 446327 |  CHEMBL3315151 | C52H65N11O11S2 | 1084.28 | 16 / 12 | -2.6 | No |
| 119365 |  CHEMBL578203 | C32H42N4O5S2 | 626.831 | 9 / 0 | 4.7 | No |
| 126760 |  CHEMBL402303 | C25H31Cl2N3O | 460.443 | 3 / 0 | 5.7 | No |
| 126762 |  CHEMBL254356 | C25H31Cl2N3O | 460.443 | 3 / 0 | 5.7 | No |
| 128927 |  CHEMBL509009 | C57H70N10O10S2 | 1119.37 | 14 / 12 | 2.2 | No |
| 130349 |  CHEMBL568388 | C36H39ClN4O6S2 | 723.3 | 10 / 1 | 6.6 | No |
| 131718 |  CHEMBL567736 | C31H38N4O6S2 | 626.787 | 10 / 1 | 4.5 | No |
| 479382 |  CHEMBL3577302 | C29H28N4O4 | 496.567 | 6 / 4 | 2.0 | Yes |
| 447291 |  CHEMBL3315148 | C52H66Cl2N10O11S2 | 1142.18 | 15 / 12 | -0.7 | No |
| 480433 |  CHEMBL3577311 | C30H32N4O4 | 512.61 | 6 / 5 | 1.6 | No |
| 480435 |  CHEMBL3577312 | C30H32N4O4 | 512.61 | 6 / 5 | 1.6 | No |
| 447351 |  CHEMBL3315139 | C52H68N10O12S2 | 1089.29 | 16 / 13 | -2.3 | No |
| 143546 |  CHEMBL390094 | C52H68N10O12S2 | 1089.29 | 16 / 13 | -2.3 | No |
| 447362 |  CHEMBL3315145 | C52H65N11O11S3 | 1116.34 | 17 / 12 | -1.8 | No |
| 480659 |  CHEMBL3577306 | C31H32N4O4 | 524.621 | 6 / 5 | 1.6 | No |
| 147868 |  CHEMBL1165764 | C47H65N11O13S2 | 1056.22 | 17 / 14 | -4.8 | No |
| 481240 |  CHEMBL3577303 | C32H32N4O4 | 536.632 | 6 / 4 | 2.7 | No |
| 447591 |  CHEMBL3315150 | C53H67N11O11S2 | 1098.31 | 16 / 12 | -2.2 | No |
| 150313 |  CHEMBL565937 | C31H35N3O4 | 513.638 | 6 / 0 | 5.1 | No |
| 156212 |  CHEMBL565580 | C36H40N4O6S2 | 688.858 | 10 / 1 | 5.6 | No |
| 156214 |  CHEMBL568316 | C36H40N4O6S2 | 688.858 | 10 / 1 | 5.6 | No |
| 156216 |  CHEMBL568165 | C36H40N4O6S2 | 688.858 | 10 / 1 | 5.6 | No |
| 159178 |  CHEMBL1165793 | C41H50N8O8S2 | 847.019 | 12 / 10 | -0.2 | No |
| 483052 |  CHEMBL3577300 | C31H30N4O4 | 522.605 | 6 / 4 | 2.3 | No |
| 166159 |  CHEMBL577772 | C47H55N9O7S2 | 922.133 | 10 / 9 | 3.3 | No |
| 171755 |  CHEMBL1165766 | C50H63N11O12S2 | 1074.24 | 15 / 13 | -1.3 | No |
| 174153 |  CHEMBL568358 | C38H48N4O6 | 656.824 | 8 / 1 | 6.0 | No |
| 176583 |  CHEMBL3104643 | C53H67N9O10S2 | 1054.29 | 14 / 11 | 1.5 | No |
| 448744 |  CHEMBL3315147 | C51H65ClN10O11S2 | 1093.71 | 15 / 12 | -1.7 | No |
| 180640 |  CHEMBL501794 | C54H75N11O10S2 | 1102.38 | 15 / 13 | 0.6 | No |
| 448814 |  CHEMBL3315153 | C51H65N11O13S2 | 1104.27 | 17 / 12 | -2.5 | No |
| 184600 |  CHEMBL236396 | C31H35N3O3 | 497.639 | 4 / 0 | 4.5 | Yes |
| 185739 |  CHEMBL1164032 | C25H32N4O6S | 516.613 | 8 / 5 | N/A | No |
| 192168 |  CHEMBL504723 | C56H69ClN10O10S2 | 1141.8 | 14 / 12 | 2.7 | No |
| 486760 |  CHEMBL3577305 | C30H30N4O4 | 510.594 | 6 / 4 | 2.3 | No |
| 202111 |  CHEMBL578205 | C32H42N6O4 | 574.726 | 7 / 2 | 3.5 | No |
| 202396 |  CHEMBL241128 | C28H36ClN5O3 | 526.078 | 6 / 2 | 2.6 | No |
| 206094 |  CHEMBL1163460 | C53H69N11O13S2 | 1132.32 | 17 / 14 | -3.2 | No |
| 210445 |  CHEMBL1165765 | C37H49N9O7S2 | 795.975 | 10 / 9 | 0.4 | No |
| 215062 |  CHEMBL452403 | C61H74N10O10S2 | 1171.44 | 14 / 12 | 3.7 | No |
| 215454 |  CHEMBL509042 | C60H72N10O10S2 | 1157.42 | 14 / 12 | 3.3 | No |
| 215610 |  CHEMBL392142 | C32H37N3O3 | 511.666 | 4 / 0 | 4.8 | No |
| 215718 |  JNJ-39319202 | C30H38N4O5S2 | 598.777 | 9 / 1 | 4.1 | No |
| 215722 |  CHEMBL1163359 | C30H38N4O5S2 | 598.777 | 9 / 1 | 4.1 | No |
| 222612 |  CHEMBL569688 | C37H46N4O6 | 642.797 | 8 / 1 | 5.6 | No |
| 223847 |  Ac-WKY-NH2 | C28H36N6O5 | 536.633 | 6 / 7 | 0.8 | No |
| 227114 |  CHEMBL568123 | C31H40N4O3S | 548.746 | 7 / 1 | 4.2 | No |
| 232262 |  CHEMBL1163467 | C59H79N13O16S2 | 1290.48 | 20 / 17 | -4.7 | No |
| 236454 |  CHEMBL571537 | C33H42N4O5S2 | 638.842 | 9 / 0 | 4.8 | No |
| 240406 |  CHEMBL1165796 | C47H55N9O7S2 | 922.133 | 10 / 9 | 3.3 | No |
| 242499 |  CHEMBL569923 | C31H40N6O6S | 624.757 | 10 / 1 | 2.9 | No |
| 242536 |  CHEMBL568637 | C31H40N4O5S2 | 612.804 | 9 / 1 | 4.5 | No |
| 246648 |  CHEMBL505358 | C61H74N10O10S2 | 1171.44 | 14 / 12 | 3.7 | No |
| 246917 |  CHEMBL391354 | C36H41ClN4O5 | 645.197 | 6 / 1 | 5.4 | No |
| 248767 |  CHEMBL510618 | C57H71ClN10O10S2 | 1155.82 | 14 / 12 | 3.1 | No |
| 248994 |  CHEMBL1165734 | C57H76N12O15S2 | 1233.42 | 19 / 16 | -4.1 | No |
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