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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL568637
Molecular formula	C31H40N4O5S2
IUPAC name	N-[(4R)-4-(3,4-dimethoxyphenyl)-4-[3-oxo-7-(4-propan-2-ylpiperazin-1-yl)-1H-isoindol-2-yl]butyl]thiophene-2-sulfonamide
Molecular weight	612.804
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50302258 SCHEMBL2342113 (R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-isopropylpiperazin-1-yl)-1-oxoisoindolin-2-yl)butyl)thiophene-2-sulfonamide
Inchi Key	OIYJVYFIYZCHNR-AREMUKBSSA-N
Inchi ID	InChI=1S/C31H40N4O5S2/c1-22(2)33-15-17-34(18-16-33)27-9-5-8-24-25(27)21-35(31(24)36)26(23-12-13-28(39-3)29(20-23)40-4)10-6-14-32-42(37,38)30-11-7-19-41-30/h5,7-9,11-13,19-20,22,26,32H,6,10,14-18,21H2,1-4H3/t26-/m1/s1
PubChem CID	25125422
ChEMBL	CHEMBL568637
IUPHAR	N/A
BindingDB	50302258
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
242535	Urotensin-2 receptor	Q9UKP6	UTS2R	Homo sapiens (Human)	389
242536	Urotensin-2 receptor	P49684	Uts2r	Rattus norvegicus (Rat)	386

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