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Ligand

NameCHEMBL1784130
Molecular formulaC21H16F4N4O
IUPAC name1-(difluoromethyl)-5-[(4S,5S)-5-(4-fluorophenyl)-5-(6-fluoropyridin-3-yl)-4-methyl-1,4-dihydroimidazol-2-yl]pyridin-2-one
Molecular weight416.38
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP2.9
Synonyms1-(difluoromethyl)-5-[(4s,5s)-4-(4-fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1h-imidazol-2-yl]pyridin-2(1h)-one
BDBM50346228
SCHEMBL3154436
5-[(4S,5S)-4-(4-Fluorophenyl)-4-(2-fluoro-5-pyridyl)-4,5-dihydro-5-methyl-1H-imidazole-2-yl]-1-(difluoromethyl)-2(1H)-pyridinone
Inchi KeyMUTOQFPGGSSVLM-QKVFXAPYSA-N
Inchi IDInChI=1S/C21H16F4N4O/c1-12-21(14-3-6-16(22)7-4-14,15-5-8-17(23)26-10-15)28-19(27-12)13-2-9-18(30)29(11-13)20(24)25/h2-12,20H,1H3,(H,27,28)/t12-,21-/m0/s1
PubChem CID10047509
ChEMBLCHEMBL1784130
IUPHARN/A
BindingDB50346228
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
214653Neuropeptide Y receptor type 1P25929NPY1RHomo sapiens (Human)384
214654Neuropeptide Y receptor type 2P49146NPY2RHomo sapiens (Human)381
214651Neuropeptide Y receptor type 4P50391NPY4RHomo sapiens (Human)375
214652Neuropeptide Y receptor type 5Q15761NPY5RHomo sapiens (Human)445

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