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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL492480
Molecular formula	C31H37N3O
IUPAC name	1-(3,4-dihydro-1H-isoquinolin-2-yl)-6-[4-(2-phenylphenyl)piperazin-1-yl]hexan-1-one
Molecular weight	467.657
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.5
Synonyms	BDBM50253130 2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline
Inchi Key	LZWDVLLURPUKQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H37N3O/c35-31(34-20-18-26-11-6-7-14-28(26)25-34)17-5-2-10-19-32-21-23-33(24-22-32)30-16-9-8-15-29(30)27-12-3-1-4-13-27/h1,3-4,6-9,11-16H,2,5,10,17-25H2
PubChem CID	25107648
ChEMBL	CHEMBL492480
IUPHAR	N/A
BindingDB	50253130
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
200418	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
200415	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
200416	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
200417	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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