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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001116168
Molecular formula	C19H15ClFN3O3S
IUPAC name	5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide
Molecular weight	419.855
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	5-chloranyl-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide SMR000625791 5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]-4-pyrimidinecarboxamide HMS2956K13 AKOS001523551 5-chloro-N-(4-fluorophenyl)-2-(2-methylbenzyl)sulfonyl-pyrimidine-4-carboxamide CHEMBL1477528 STK517433 5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide MCULE-2267422856 BDBM54506 MolPort-000-542-293 5-chloro-N-(4-fluorophenyl)-2-[(2-methylbenzyl)sulfonyl]pyrimidine-4-carboxamide cid_16452954 ZINC9206947 MLS-0363689.0001 [ Show all ]
Inchi Key	LIEQNFQFBUWUFS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H15ClFN3O3S/c1-12-4-2-3-5-13(12)11-28(26,27)19-22-10-16(20)17(24-19)18(25)23-15-8-6-14(21)7-9-15/h2-10H,11H2,1H3,(H,23,25)
PubChem CID	16452954
ChEMBL	CHEMBL1477528
IUPHAR	N/A
BindingDB	54506
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
188131	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
188128	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
188129	C-X-C chemokine receptor type 5	P32302	CXCR5	Homo sapiens (Human)	372
188130	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
188127	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
188126	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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