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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TAN-67
Molecular formula	C23H24N2O
IUPAC name	3-[(4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a-yl]phenol
Molecular weight	344.458
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.3
Synonyms	SB-205,607 C20168 (-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol CHEMBL327745 3-((4aS,12aR)-2-Methyl-1,3,4,5,12,12a-hexahydro-2H-2,6-diaza-naphthacen-4a-yl)-phenol SB-213698 CHEBI:124990 ZINC3995327 (-)-TAN-67 GTPL9567 3-[(4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a-yl]phenol BDBM50290872 SCHEMBL12013211 (-)TAN-67 [ Show all ]
Inchi Key	LEPBHAAYNPPRRA-WMZHIEFXSA-N
Inchi ID	InChI=1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m0/s1
PubChem CID	9950038
ChEMBL	CHEMBL327745
IUPHAR	9567
BindingDB	50290872
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
185471	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
185473	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
185474	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
185470	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
185475	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
526812	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
185472	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
185476	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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