Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	RU 24969
Molecular formula	C14H16N2O
IUPAC name	5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Molecular weight	228.295
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.8
Synonyms	FT-0745673 NCGC00024867-01 ZINC2568243 5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole(RU-24969) AC1Q4F1Q BDBM81498 CTK1J4546 KRVMLPUDAOWOGN-UHFFFAOYSA-N NSC_108028 SCHEMBL2359264 2ISE72RACC 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole CAS_108028 DTXSID40276045 MCULE-3532976182 PDSP2_001601 Tocris-0912 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridyl)-1h-indole AB00698348-04 CHEMBL18785 GTPL23 NCGC00024867-02 RU-24,969 1H-Indole, 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)- 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole AKOS005135871 Biomol-NT_000116 D03PJW L001328 PDSP1_001617 SR-01000597981 3-(1,2,3,6-tetrahydropyridin-4-yl)-5-methoxy-1H-indole 66611-26-5 CHEBI:92005 EN300-39806 MolPort-003-983-322 PDSP2_001607 UNII-2ISE72RACC 5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole AC1L337E CS-3218 HY-16688 NE18708 RU-24969 5-methoxy-3-(1,2,3,6-tetrahydropyridine-4-yl)-1H-indole API0006969 BPBio1_000177 DB-073775 LS-187325 PDSP1_001623 SR-01000597981-1 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole [ Show all ]
Inchi Key	KRVMLPUDAOWOGN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16N2O/c1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10/h2-4,8-9,15-16H,5-7H2,1H3
PubChem CID	108029
ChEMBL	CHEMBL18785
IUPHAR	23
BindingDB	81498
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
176686	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
176693	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
176685	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
176689	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
176700	5-hydroxytryptamine receptor 1B	P28334	Htr1b	Mus musculus (Mouse)	386
176688	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
176694	5-hydroxytryptamine receptor 1D	P11614	HTR1D	Canis lupus familiaris (Dog)	377
176699	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
176702	5-hydroxytryptamine receptor 1F	Q02284	Htr1f	Mus musculus (Mouse)	366
176697	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556178	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
176684	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
176698	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
176691	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
176690	5-hydroxytryptamine receptor 5A	P30966	Htr5a	Mus musculus (Mouse)	357
554176	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
176692	5-hydroxytryptamine receptor 5B	P31387	Htr5b	Mus musculus (Mouse)	370
176696	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
176701	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
554175	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417