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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL82374
Molecular formula	C22H28FN3O2S
IUPAC name	1-[4-[[(9-fluoro-4,5-dihydro-[1]benzoxepino[5,4-d][1,3]thiazol-2-yl)amino]methyl]piperidin-1-yl]pentan-1-one
Molecular weight	417.543
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50145236 SCHEMBL7993308 1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-pentan-1-one
Inchi Key	KOGZUICFSKKHFC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28FN3O2S/c1-2-3-4-20(27)26-10-7-15(8-11-26)14-24-22-25-21-17-13-16(23)5-6-18(17)28-12-9-19(21)29-22/h5-6,13,15H,2-4,7-12,14H2,1H3,(H,24,25)
PubChem CID	10295464
ChEMBL	CHEMBL82374
IUPHAR	N/A
BindingDB	50145236
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174042	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
174041	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
174044	Neuropeptide Y receptor type 4	P50391	NPY4R	Homo sapiens (Human)	375
174040	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445
174043	Neuropeptide Y receptor type 5	Q63634	Npy5r	Rattus norvegicus (Rat)	445

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