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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(S)-Metoprolol
Molecular formula	C15H25NO3
IUPAC name	(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Molecular weight	267.369
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.9
Synonyms	BDBM81881 KB-210701 (S)-(-)-Metoprolol (S)-Metoprorol AE-562/11525411 CHEMBL148306 s-metoprolol 2587AC ANW-73228 FT-0672383 UNII-GEB06NHM23 component IUBSYMUCCVWXPE-AWEZNQCLSA-N (2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol (S)-1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol 91324-86-6 C-23812 l-Metoprolol 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol AJ-26685 CTK8C4817 SCHEMBL121589 (-)-Metoprolol 81024-42-2 API0005937 IUBSYMUCCVWXPE-AWEZNQCLSA-N ZINC1530717 (2S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol AC1L4IJQ MCULE-4106696689 2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (2S)- AKOS016008513 DTXSID60230861 TC-161973 (-)metoprolol [ Show all ]
Inchi Key	IUBSYMUCCVWXPE-AWEZNQCLSA-N
Inchi ID	InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3/t14-/m0/s1
PubChem CID	157716
ChEMBL	CHEMBL148306
IUPHAR	N/A
BindingDB	81881
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
141812	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
141810	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
141811	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418
460506	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418

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