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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1084552
Molecular formula	C26H20ClF3N2O4
IUPAC name	4-[(1S)-1-[[1-[[3-chloro-5-(trifluoromethoxy)phenyl]methyl]indole-7-carbonyl]amino]ethyl]benzoic acid
Molecular weight	516.901
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.1
Synonyms	BDBM50319840 (S)-4-(1-(1-(3-chloro-5-(trifluoromethoxy)benzyl)-1H-indole-7-carboxamido)ethyl)benzoic acid
Inchi Key	HQCZRLVYPNLNQN-HNNXBMFYSA-N
Inchi ID	InChI=1S/C26H20ClF3N2O4/c1-15(17-5-7-19(8-6-17)25(34)35)31-24(33)22-4-2-3-18-9-10-32(23(18)22)14-16-11-20(27)13-21(12-16)36-26(28,29)30/h2-13,15H,14H2,1H3,(H,31,33)(H,34,35)/t15-/m0/s1
PubChem CID	46890658
ChEMBL	CHEMBL1084552
IUPHAR	N/A
BindingDB	50319840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
121274	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
121267	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
121269	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
121272	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
121273	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
121271	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
121270	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
121268	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
121275	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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