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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEBI:75204
Molecular formula	C8H9NO4
IUPAC name	(2S)-2-azaniumyl-2-(3,5-dihydroxyphenyl)acetate
Molecular weight	183.163
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	-1.8
Synonyms	L-(3,5-dihydroxyphenyl)glycine (2S)-azaniumyl(3,5-dihydroxyphenyl)acetate (S)-3,5-dihydroxyphenylglycine zwitterion
Inchi Key	HOOWCUZPEFNHDT-ZETCQYMHSA-N
Inchi ID	InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)/t7-/m0/s1
PubChem CID	71668376
ChEMBL	CHEMBL39221
IUPHAR	N/A
BindingDB	50079183
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
120216	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
120220	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
120221	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
120226	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
120217	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
120218	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
120223	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
120225	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
120219	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908
120222	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
120224	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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