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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	137403-12-4
Molecular formula	C20H21N5O3S
IUPAC name	N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide
Molecular weight	411.48
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.2
Synonyms	DTXSID20160175 L000336 NCGC00024787-02 VZ23436 AC1L30BK BN0648 CHEBI:92341 J-007018 Methanesulfonamide,N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]- RTX-011688 2-(5-(3-(4-(Methylsulfonylamino)benzyl)-1,2,4-oxadiazol-5-yl)-1H-indole-3-yl)ethylamine API0007693 CTK8B8457 L-694,247 N-[4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide SR-01000597694-1 BDBM50406771 GTPL15 L694247 PDSP1_001394 ZINC3797946 AKOS016003154 BPBio1_000001 KB-258171 MolPort-003-943-292 SCHEMBL1321182 2-[5-[3-(4-Methylsulfonylamino)benzyl-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethanamine AX8232748 D0G1RT L-694247 NCGC00024787-01 Tocris-0781 6580AA Biomol-NT_000112 HMS3266D14 Methanesulfonamide, N-(4-((5-(3-(2-aminoethyl)-1H-indol-5-yl)-1,2,4-oxadiazol-3-yl)methyl)phenyl)- PDSP2_001378 ANW-60396 BRD-K18816859-001-01-4 CHEMBL39317 L 694247 N-(4-((5-(3-(2-Aminoethyl)-1H-indol-5-yl)-1,2,4-oxadiazol-3-yl)methyl)phenyl)methanesulfonamide SR-01000597694 4CA-0715 B6451 [ Show all ]
Inchi Key	HKXMQLISPYELRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21N5O3S/c1-29(26,27)25-16-5-2-13(3-6-16)10-19-23-20(28-24-19)14-4-7-18-17(11-14)15(8-9-21)12-22-18/h2-7,11-12,22,25H,8-10,21H2,1H3
PubChem CID	132059
ChEMBL	CHEMBL39317
IUPHAR	15
BindingDB	50406771
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
117593	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
553865	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
117596	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
553864	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
117594	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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