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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL496327
Molecular formula	C21H19N3O4
IUPAC name	methyl 2-(3-oxospiro[2-benzofuran-1,4'-piperidine]-1'-yl)-3H-benzimidazole-5-carboxylate
Molecular weight	377.4
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.3
Synonyms	SCHEMBL6453626 BDBM50265298 methyl 2-(3-oxo-3H-spiro[isobenzofuran-1,4''-piperidine]-1''-yl)-1H-benzo[d]imidazole-5-carboxylate
Inchi Key	HEZGTATZCDHJOU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19N3O4/c1-27-18(25)13-6-7-16-17(12-13)23-20(22-16)24-10-8-21(9-11-24)15-5-3-2-4-14(15)19(26)28-21/h2-7,12H,8-11H2,1H3,(H,22,23)
PubChem CID	20587808
ChEMBL	CHEMBL496327
IUPHAR	N/A
BindingDB	50265298
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
113261	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
113260	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
113259	Neuropeptide Y receptor type 4	P50391	NPY4R	Homo sapiens (Human)	375
113258	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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