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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL251835
Molecular formula	C26H27BrN6O2
IUPAC name	[(6aR,9R,10aR)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]-[4-(2,1,3-benzoxadiazol-5-yl)piperazin-1-yl]methanone
Molecular weight	535.446
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50423462
Inchi Key	GZFMZJDVLOZLLL-OMXJDXKCSA-N
Inchi ID	InChI=1S/C26H27BrN6O2/c1-31-14-15(11-18-17-3-2-4-21-24(17)19(13-23(18)31)25(27)28-21)26(34)33-9-7-32(8-10-33)16-5-6-20-22(12-16)30-35-29-20/h2-6,12,15,18,23,28H,7-11,13-14H2,1H3/t15-,18-,23-/m1/s1
PubChem CID	44447073
ChEMBL	CHEMBL251835
IUPHAR	N/A
BindingDB	50423462
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
108952	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
108949	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
108955	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
108950	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
108956	Somatostatin receptor type 1	P28646	Sstr1	Rattus norvegicus (Rat)	391
108953	Somatostatin receptor type 2	P30680	Sstr2	Rattus norvegicus (Rat)	369
108957	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
108954	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
108948	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
108951	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364

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