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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(S)-4-CARBOXY-3-HYDROXYPHENYLGLYCINE
Molecular formula	C9H9NO5
IUPAC name	4-[(S)-amino(carboxy)methyl]-2-hydroxybenzoic acid
Molecular weight	211.173
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-1.0
Synonyms	CHEMBL39372 PDSP1_001316 ZINC2559031 4-((S)-Amino-carboxy-methyl)-2-hydroxy-benzoic acid AKOS024457474 DFS3SIU1ME SR-01000597633 (S)-4-(amino(carboxy)methyl)-2-hydroxybenzoic acid 4-[(1S)-1-amino-2-hydroxy-2-oxoethyl]-2-hydroxybenzoic acid BDBM50053585 BN0022 NCGC00024532-01 UNII-DFS3SIU1ME (s)-4C3HPG 85148-82-9 CTK8F2145 PDSP2_001300 4-Carboxy-3-hydroxy-L-phenylglycine B6253 Benzeneacetic acid, alpha-amino-4-carboxy-3-hydroxy-, (alphaS)- GTPL1374 SR-01000597633-1 4C3HPG NCGC00024532-02 UNII-M725GQ103A component GXZSAQLJWLCLOX-ZETCQYMHSA-N AC1NSKO9 D0S6DK SCHEMBL12648356 4-Carboxy-3-hydroxyphenylglycine, (S)- B6255 Benzeneacetic acid, alpha-amino-4-carboxy-3-hydroxy-, (S)- MolPort-003-983-491 Tocris-0320 (S)-4C3H-PG [ Show all ]
Inchi Key	GXZSAQLJWLCLOX-ZETCQYMHSA-N
Inchi ID	InChI=1S/C9H9NO5/c10-7(9(14)15)4-1-2-5(8(12)13)6(11)3-4/h1-3,7,11H,10H2,(H,12,13)(H,14,15)/t7-/m0/s1
PubChem CID	5311455
ChEMBL	CHEMBL39372
IUPHAR	1374
BindingDB	50053585
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
108029	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
108030	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
108026	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
108027	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
108031	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
553787	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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