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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL598198
Molecular formula	C25H22F3N5OS
IUPAC name	2,5-dimethyl-N-[1-[4-(2H-tetrazol-5-yl)phenyl]cyclopropyl]-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carboxamide
Molecular weight	497.54
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.5
Synonyms	SCHEMBL2351426 BDBM144440 2,5-Dimethyl-N-{1-[4-(2H-tetrazol-5-yl)phenyl]cyclopropyl}-4-[4-(trifluoromethyl)benzyl]thiophene-3-carboxamide US8969394, 14 BDBM50308132 FMLJGBDOSCBJBZ-UHFFFAOYSA-N [ Show all ]
Inchi Key	FMLJGBDOSCBJBZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22F3N5OS/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)35-14)23(34)29-24(11-12-24)18-9-5-17(6-10-18)22-30-32-33-31-22/h3-10H,11-13H2,1-2H3,(H,29,34)(H,30,31,32,33)
PubChem CID	24952928
ChEMBL	CHEMBL598198
IUPHAR	N/A
BindingDB	144440, 50308132
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
82011	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
82012	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
82006	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
82007	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
82009	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
82004	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
82005	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
82010	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
82008	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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