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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL469821
Molecular formula	C28H34N2O4S
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-2-(2-methylpropyl)-N-methylsulfonylbenzamide
Molecular weight	494.65
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.7
Synonyms	BDBM50277531 SCHEMBL4584104 4''-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-3-isobutyl-N-(methylsulfonyl)biphenyl-4-carboxamide Hydrochloride CHEMBL1186563
Inchi Key	FKGYWDPSUXSSQK-MHZLTWQESA-N
Inchi ID	InChI=1S/C28H34N2O4S/c1-20(2)17-25-18-24(13-14-26(25)28(32)30-35(3,33)34)22-11-9-21(10-12-22)15-16-29-19-27(31)23-7-5-4-6-8-23/h4-14,18,20,27,29,31H,15-17,19H2,1-3H3,(H,30,32)/t27-/m0/s1
PubChem CID	11340895
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50277531
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
80417	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
459949	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
80415	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
80416	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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