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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL120055
Molecular formula	C23H28N4O2
IUPAC name	2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]-1-[4-(2-methylphenyl)piperazin-1-yl]ethanone
Molecular weight	392.503
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.8
Synonyms	1-[4-[2-Methylphenyl]piperazin-1-yl]-2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]ethanone BDBM50033447 L011210 2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-tolyl-piperazin-1-yl)-ethanone
Inchi Key	DWSOZYFSYVOVOC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N4O2/c1-17-4-2-3-5-22(17)26-10-12-27(13-11-26)23(28)16-29-19-6-7-21-20(14-19)18(8-9-24)15-25-21/h2-7,14-15,25H,8-13,16,24H2,1H3
PubChem CID	10385855
ChEMBL	CHEMBL120055
IUPHAR	N/A
BindingDB	50033447
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70846	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
70848	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
70849	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
70850	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
70847	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
70853	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
70851	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
70854	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
70852	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479

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