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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2420779
Molecular formula	C18H23N3O
IUPAC name	1-(2-ethoxyphenyl)-4-(pyridin-3-ylmethyl)piperazine
Molecular weight	297.402
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.6
Synonyms	AB00044705-01 MolPort-002-140-989 BDBM50439455 SR-01000201893-1 1-(2-ethoxyphenyl)-4-(pyridin-3-ylmethyl)piperazine AB00044705-02 Oprea1_682548 Cambridge id 5262610 ZINC55543289 MCULE-2428184748 AC1LGCQ5 SR-01000201893 [ Show all ]
Inchi Key	CNFWITKOFBJCHE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23N3O/c1-2-22-18-8-4-3-7-17(18)21-12-10-20(11-13-21)15-16-6-5-9-19-14-16/h3-9,14H,2,10-13,15H2,1H3
PubChem CID	792584
ChEMBL	CHEMBL2420779
IUPHAR	N/A
BindingDB	50439455
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46004	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
46005	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
46003	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
46006	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
46002	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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