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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL74594
Molecular formula	C20H29N5O
IUPAC name	1-[(E)-[5-(3-methylbut-2-enoxy)-1H-indol-3-yl]methylideneamino]-2-pentylguanidine
Molecular weight	355.486
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	4.1
Synonyms	BDBM50453700
Inchi Key	BSTFUTCMSPDNRH-ZVHZXABRSA-N
Inchi ID	InChI=1S/C20H29N5O/c1-4-5-6-10-22-20(21)25-24-14-16-13-23-19-8-7-17(12-18(16)19)26-11-9-15(2)3/h7-9,12-14,23H,4-6,10-11H2,1-3H3,(H3,21,22,25)/b24-14+
PubChem CID	135500023
ChEMBL	CHEMBL74594
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558259	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
558256	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
558258	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
558257	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
558260	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388

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