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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	8-Leu-9-des-arg-BK
Molecular formula	C41H63N11O10
IUPAC name	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoic acid
Molecular weight	870.022
Hydrogen bond acceptor	12
Hydrogen bond donor	9
XlogP	-3.6
Synonyms	2-{[1-(2-{2-[2-({1-[1-(2-Amino-5-guanidino-pentanoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonyl}-amino)-acetylamino]-3-phenyl-propionylamino}-3-hydroxy-propionyl)-pyrrolidine-2-carbonyl]-amino}-4-methyl-pentanoic acid Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu D00FUT 64695-06-3 Bradykinin, leu(8) (1-8) LS-182509 (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpe AC1L3XHA [Leu...8...][des-Arg...9...]Bradykinin BDBM50089306 DALBK 8-Leu-9-de-arg-bradykinin bradykinin, Leu(8)-des-Arg(9)- NCGC00167253-01 (S)-2-((S)-1-((S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-Amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoyl)pyrrolidine-2-carboxamido)-4-methylpentanoic acid AKOS027382079 CHEMBL80472 [Leu8,des-Arg9]bradykinin Bradykinin, 8-L-leucine-9-de-L-arginine- GTPL641 Bradykinin, leucyl(8)-des-arginine(9)- ZINC169326759 [ Show all ]
Inchi Key	BGAPYBBQGHUQNM-YYGRSCHNSA-N
Inchi ID	InChI=1S/C41H63N11O10/c1-24(2)20-28(40(61)62)48-36(57)31-14-8-17-50(31)38(59)29(23-53)49-34(55)27(21-25-10-4-3-5-11-25)47-33(54)22-46-35(56)30-13-7-18-51(30)39(60)32-15-9-19-52(32)37(58)26(42)12-6-16-45-41(43)44/h3-5,10-11,24,26-32,53H,6-9,12-23,42H2,1-2H3,(H,46,56)(H,47,54)(H,48,57)(H,49,55)(H,61,62)(H4,43,44,45)/t26-,27-,28-,29-,30-,31-,32-/m0/s1
PubChem CID	123884
ChEMBL	CHEMBL80472
IUPHAR	641
BindingDB	50089306
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22794	B1 bradykinin receptor	P46663	BDKRB1	Homo sapiens (Human)	353
553348	B1 bradykinin receptor	Q61125	Bdkrb1	Mus musculus (Mouse)	334
553349	B1 bradykinin receptor	P97583	Bdkrb1	Rattus norvegicus (Rat)	337
22795	B2 bradykinin receptor	P30411	BDKRB2	Homo sapiens (Human)	391

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