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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL281274
Molecular formula	C25H25N3O
IUPAC name	8-(1,2-dihydroacenaphthylen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	383.495
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.5
Synonyms	1-Phenyl-8-(acenaphthen-1-yl)-1,3,8-triazaspiro[4.5]decan-4-one SCHEMBL2248376 8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one BDBM50087016 Ro65-6570 8-(1,2-dihydroacenaphthylen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one [ Show all ]
Inchi Key	BBOAHBVXCYBKLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25N3O/c29-24-25(28(17-26-24)20-9-2-1-3-10-20)12-14-27(15-13-25)22-16-19-8-4-6-18-7-5-11-21(22)23(18)19/h1-11,22H,12-17H2,(H,26,29)
PubChem CID	10022859
ChEMBL	CHEMBL281274
IUPHAR	N/A
BindingDB	50087016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19679	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
19681	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
19680	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
19678	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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