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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL271913
Molecular formula	C27H37ClN4O3
IUPAC name	1-(5-chloro-2-methoxyphenyl)-3-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]cyclohexyl]urea
Molecular weight	501.068
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.3
Synonyms	CAS_16041451 NSC_16041451 SCHEMBL13866674 BDBM86844 1-(5-chloro-2-methoxyphenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea SCHEMBL13866681 [ Show all ]
Inchi Key	AVIOZEGAUFSOTR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H37ClN4O3/c1-19(2)35-26-7-5-4-6-24(26)32-16-14-31(15-17-32)22-11-9-21(10-12-22)29-27(33)30-23-18-20(28)8-13-25(23)34-3/h4-8,13,18-19,21-22H,9-12,14-17H2,1-3H3,(H2,29,30,33)
PubChem CID	16041451
ChEMBL	CHEMBL271913
IUPHAR	N/A
BindingDB	86844
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15326	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
15324	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
15325	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
15323	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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