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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL306218
Molecular formula	C21H20N2O4
IUPAC name	3-methoxy-2-(4-methylpyrimidin-2-yl)oxy-3,3-diphenylpropanoic acid
Molecular weight	364.401
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.4
Synonyms	MolPort-002-937-635 AC1NP1UH 3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid MCULE-3842146851 3-Methoxy-3,3-diphenyl-2-[(4-methylpyrimidin-2-yl)oxy]propanoic acid AKOS005385984 SMR000503066 3-methoxy-2-(4-methylpyrimidin-2-yl)oxy-3,3-diphenylpropanoic acid MLS001195209 BDBM50050810 STK055081 HMS2843E10 3-methoxy-2-[(4-methylpyrimidin-2-yl)oxy]-3,3-diphenylpropanoic acid [ Show all ]
Inchi Key	AIHUUIAJRNWVGQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20N2O4/c1-15-13-14-22-20(23-15)27-18(19(24)25)21(26-2,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-14,18H,1-2H3,(H,24,25)
PubChem CID	5122650
ChEMBL	CHEMBL306218
IUPHAR	N/A
BindingDB	50050810
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6224	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
6226	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
6225	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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