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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS002156773
Molecular formula	C23H20FN5O2S
IUPAC name	4-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-2-pyridin-3-ylquinazoline
Molecular weight	449.504
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.3
Synonyms	AKOS021972774 SMR001239275 4-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-2-(pyridin-3-yl)quinazoline HMS3051P06 AB00755236-01 MolPort-004-179-077 Z31102959 4-{4-[(4-fluorophenyl)sulfonyl]piperazino}-2-(3-pyridyl)quinazoline MCULE-5749552167 AB00755236-06 NCGC00287735-01 CHEMBL1494017 ZINC13117401 920911-45-1 [ Show all ]
Inchi Key	AIEZKTDMVNDTBE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H20FN5O2S/c24-18-7-9-19(10-8-18)32(30,31)29-14-12-28(13-15-29)23-20-5-1-2-6-21(20)26-22(27-23)17-4-3-11-25-16-17/h1-11,16H,12-15H2
PubChem CID	16319239
ChEMBL	CHEMBL1494017
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6155	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
6154	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332

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