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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5HT6-ligand-1
Molecular formula	C20H22BrN3O2S
IUPAC name	1-(2-bromophenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole
Molecular weight	448.379
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.6
Synonyms	SCHEMBL3216224 BDBM50402702 CS-7163 HY-U00126 CHEMBL2207386
Inchi Key	AGKMPGSBLMAGAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22BrN3O2S/c1-22-11-13-23(14-12-22)15-16-5-4-7-19-17(16)9-10-24(19)27(25,26)20-8-3-2-6-18(20)21/h2-10H,11-15H2,1H3
PubChem CID	24965679
ChEMBL	CHEMBL2207386
IUPHAR	N/A
BindingDB	50402702
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4955	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
4953	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
4952	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
4957	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
4956	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
4954	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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