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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL232206
Molecular formula	C29H26F3N5S
IUPAC name	10-[[4-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]phenyl]methyl]-2-(trifluoromethyl)phenothiazine
Molecular weight	533.617
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	6.2
Synonyms	N/A
Inchi Key	AGFDEJVDCUGXTG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H26F3N5S/c30-29(31,32)23-10-11-27-25(18-23)37(24-4-1-2-5-26(24)38-27)20-22-8-6-21(7-9-22)19-35-14-16-36(17-15-35)28-33-12-3-13-34-28/h1-13,18H,14-17,19-20H2
PubChem CID	44431668
ChEMBL	CHEMBL232206
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4829	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
4830	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
441895	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
4828	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
4826	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
4827	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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