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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000118160
Molecular formula	C20H18N4O3
IUPAC name	1-(3-amino-7-methoxypyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone
Molecular weight	362.389
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.2
Synonyms	HMS2252E23 SR-01000097404 AKOS001823279 MCULE-1602443054 1-(3-amino-7-methoxypyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone cid_5307507 MolPort-007-647-651 7-methoxy-1-[(2-methoxyphenyl)acetyl]-1H-pyrazolo[3,4-b]quinolin-3-amine HMS3441P08 SR-01000097404-1 1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-2-(2-methoxyphenyl)ethanone BDBM48966 1-(3-azanyl-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone CHEMBL1538218 HMS1388E08 SMR000095108 AC1NSCOX IDI1_005499 ZINC4939962 1-(3-amino-7-methoxy-pyrazolo[3,4-b]quinolin-1-yl)-2-(2-methoxyphenyl)ethanone CHEBI:108975 ChemDiv2_006784 MLS002587577 [ Show all ]
Inchi Key	AFARTCQWZVTVJO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18N4O3/c1-26-14-8-7-12-9-15-19(21)23-24(20(15)22-16(12)11-14)18(25)10-13-5-3-4-6-17(13)27-2/h3-9,11H,10H2,1-2H3,(H2,21,23)
PubChem CID	5307507
ChEMBL	CHEMBL1538218
IUPHAR	N/A
BindingDB	48966
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4000	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
3999	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
4001	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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