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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	D-Tetrahydropalmatine
Molecular formula	C21H25NO4
IUPAC name	(13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Molecular weight	355.434
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	tetrahydropalmatine (13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline 6H-Dibenzo[a,g]quinolizine,5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aR)- DTXSID80359548 UNII-78F8583LNQ component AEQDJSLRWYMAQI-QGZVFWFLSA-N (+)-(R)-Tetrahydropalmatine 13abeta-Berbine, 2,3,9,10-tetramethoxy- MCULE-1328768112 ZINC19535046 (+)-Tetrahydropalmatine 520T147 corydalis B Rotundine Tetrahydropalmatine D-form [MI] (13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine 7BLG4NXS54 FT-0675040 UNII-7BLG4NXS54 (+)-2,3,9,10-Tetramethoxyberbine 2,3,9,10-Tetramethoxy-13a\|A-berbine CHEMBL2334889 MolPort-001-728-103 SCHEMBL2742488 (+)-Tetrahydropalmatine Alkaloid 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aR)- Tetrahydropalmatine, (+)- (R)-Tetrahydropalmatine AC1LJ6RP I14-18854 Y0073 (+)-Corydalis B 3520-14-7 Corydalis alkaloid B N1188 [ Show all ]
Inchi Key	AEQDJSLRWYMAQI-QGZVFWFLSA-N
Inchi ID	InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1
PubChem CID	969488
ChEMBL	CHEMBL2334889
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3745	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
3744	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
3746	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
3747	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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