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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Neuromedin-K receptor
Species	Mus musculus (Mouse)
Gene	Tacr3
Synonym	Tac3r SP-N receptor Nmkr NKR NK3 receptor NK-3R NK-3 receptor neuromedin K receptor neurokinin beta receptor Neurokinin B receptor Tachykinin receptor 3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MASVPTGENWTDGTAGVGSHTGNLSAALGITEWLALQAGNFSSALGLPVTSQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLVNFIYGVHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLYDPSEGDPAKSSRKKRAVPRDPSANGCSHREFKSASTTSSFISSPYTSVDEYS
UniProt	P47937
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	362
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
553258	Substance P	C63H98N18O13S	1347.65	17 / 15	-2.3	No
459886	CHEMBL299377	C35H41Cl2N3O2	606.632	3 / 0	7.0	No
553819	NEUROKININ A	C50H80N14O14S	1133.33	18 / 16	-4.8	No
553870	Senktide	C40H55N7O11S	841.978	12 / 8	1.1	No
460867	NKB [MePhe7]	C56H81N13O14S2	1224.46	18 / 13	-1.4	No
461060	GR 113808	C19H27N3O4S	393.502	6 / 1	1.7	Yes
554383	Neurokinin B	C55H79N13O14S2	1210.43	18 / 14	-1.6	No
461510	venlafaxine	C17H27NO2	277.408	3 / 1	2.9	Yes
461764	SB 235375	C27H24N2O4	440.499	5 / 2	5.1	No
461794	BCTC	C20H25ClN4O	372.897	3 / 1	4.3	Yes
461816	abt-702	C22H19BrN6O	463.339	7 / 1	3.4	Yes
462277	N-Methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine	C17H21NO	255.361	2 / 1	3.7	Yes
462836	duloxetine	C18H19NOS	297.416	3 / 1	4.3	Yes
462887	Burapitant	C31H35Cl2F6N3O3	682.529	10 / 1	6.2	No

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