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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB 235375
Molecular formula	C27H24N2O4
IUPAC name	2-[2-phenyl-4-[[(1S)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetic acid
Molecular weight	440.499
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.1
Synonyms	Acetic acid, ((2-phenyl-4-((((1S)-1-phenylpropyl)amino)carbonyl)-3-quinolinyl)oxy)- GTPL5772 (-)-(S)-N-(alpha-Ethylbenzyl)-3-(carboxymethoxy)-2-phenylquinoline-4-carboxamide PDSP1_000973 Acetic acid, ((2-phenyl-4-(((1-phenylpropyl)amino)carbonyl)-3-quinolinyl)oxy)-, (S)- SB-235375 LS-12763 2-[2-phenyl-4-[[(1S)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetic Acid PDSP2_000957 BDBM85845 SCHEMBL6224799 N-[(S)-1-Phenylpropyl]-2-phenyl-3-(carboxymethoxy)quinoline-4-carboxamide 224961-34-6 [ Show all ]
Inchi Key	RJIWGNBRTQFKBW-NRFANRHFSA-N
Inchi ID	InChI=1S/C27H24N2O4/c1-2-21(18-11-5-3-6-12-18)29-27(32)24-20-15-9-10-16-22(20)28-25(19-13-7-4-8-14-19)26(24)33-17-23(30)31/h3-16,21H,2,17H2,1H3,(H,29,32)(H,30,31)/t21-/m0/s1
PubChem CID	9846078
ChEMBL	N/A
IUPHAR	5772
BindingDB	85845
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
297618	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
297622	Neuromedin-K receptor	P30098	TACR3	Cavia porcellus (Guinea pig)	440
461764	Neuromedin-K receptor	P47937	Tacr3	Mus musculus (Mouse)	452
297619	Substance-K receptor	Q64077	TACR2	Cavia porcellus (Guinea pig)	402
556641	Substance-K receptor	P16610	Tacr2	Rattus norvegicus (Rat)	390

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