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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355951
Molecular formula	C30H32F2N2S
IUPAC name	2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-1-phenylindole
Molecular weight	490.657
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	7.8
Synonyms	YWGYONXMCGHURW-UHFFFAOYSA-N BDBM50041190 SCHEMBL2564463 2-ETHYL-6-FLUORO-3-{1-[3-(4-FLUOROPHENYLSULFANYL)-PROPYL]-PIPERIDIN-4-YL}-1-PHENYL-1H-INDOLE
Inchi Key	YWGYONXMCGHURW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H32F2N2S/c1-2-28-30(27-14-11-24(32)21-29(27)34(28)25-7-4-3-5-8-25)22-15-18-33(19-16-22)17-6-20-35-26-12-9-23(31)10-13-26/h3-5,7-14,21-22H,2,6,15-20H2,1H3
PubChem CID	11952524
ChEMBL	CHEMBL3355951
IUPHAR	N/A
BindingDB	50041190
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
458387	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
458388	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
458389	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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