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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3236568
Molecular formula	C11H19N5
IUPAC name	4-ethyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Molecular weight	221.308
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	0.9
Synonyms	BDBM50006758 SCHEMBL603036
Inchi Key	YTSCCHQLULFXJD-SECBINFHSA-N
Inchi ID	InChI=1S/C11H19N5/c1-3-8-6-10(15-11(12)14-8)16-5-4-9(7-16)13-2/h6,9,13H,3-5,7H2,1-2H3,(H2,12,14,15)/t9-/m1/s1
PubChem CID	42624149
ChEMBL	CHEMBL3236568
IUPHAR	N/A
BindingDB	50006758
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
419076	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
419074	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
419075	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391

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